Throughout a busy week, it is impossible to manage different work with bank related work. Like other banks Muslim Commercial Bank branches are open for their respected costumers on Saturday. While most Muslim Commercial branches are closed on Saturdays, here are a few that will remain open on the first day of the weekend. The MCB branches open on Saturday in different regions are as follow
| NO | B. Code | Branch Name | Region | Circle | Phone Number |
| 01 | 0088 | Marich Bazar Sukkur | Sukkur | Sukkur | 071-5628626,5627812 |
| 02 | 0101 | Clock Tower Sukkur | Sukkur | Sukkur | 071-5621553,5626591 |
| 03 | 0082 | Khairpur Mirs | Sukkur | Sukkur | 0243-715812 |
| 04 | 0126 | Ghotki | Sukkur | Sukkur | 0723-681028 |
| 05 | 0104 | Dhurki | Sukkur | Sukkur | 0723-642902 |
| 06 | 0088 | Anaj Mandi Larkana | Larkana | Sukkur | 071-5628626, |
| 07 | 0931 | Pakistan Chowk Larkana | Larkana | Sukkur | 074-4059141 |
| 08 | 0087 | Shikarpur Anaj Mandi | Larkana | Sukkur | 0726-520454 |
| 09 | 0095 | Dadu | Larkana | Sukkur | 0254-610971 |
| 10 | 0098 | Shahdad Kot | Larkana | Sukkur | 74-4014946 |
